Translational Neurophysiology & Brain Stimulation
The Toronto Western Hospital is a pioneering center for a neurosurgical procedure called deep brain stimulation (DBS). DBS is a standard of care procedure for patients with Parkinson's disease, essential tremor, dystonia, and has garnered much attention for many other refractory neurological disorders. The Toronto Western Hospital is also home of the Krembil Brain Institute and our Translational Neurophysiology and Brain Stimulation (TNBS) research laboratory. The TNBS team is committed to to understanding human brain function and dysfunction, and to the development of new brain stimulation methods to improve patient care.
The TNBS Lab, physically located at the Krembil Brain Institute, consists of wet and dry lab space and a permanent fixture within a state-of-the-art operating theater known as the CRANIA Neuromodulation Suite.
The TNBS team consists of students enrolled in graduate programs at University of Toronto as well as Postdoctoral Fellows and Research personnel directly appointed at the Krembil Brain Institute. We moreover proudly collaborate with a multidisciplinary team of neurosurgeons, neurologists, engineers, computational neuroscientists, basic physiologists, and more.
Our research generally involves the acquisition and analysis of neural data from patients undergoing awake brain surgery. We collect intracranial recordings (i.e. single-neuron and local field potential activity from subcortical nuclei and electrocorticography from the surface of the brain) in the context of various research projects (i.e. behavioural tasks, brain stimulation, brain-computer interfaces, synaptic plasticity, etc.).
Prospective students and researchers with experience and/or interest in neuromodulation, signal processing, machine learning, computational neuroscience, instrumentation, and/or brain-machine interfaces can contact Dr. Milosevic by email at any time.